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RNS Number : 6891N
Shield Therapeutics PLC
26 September 2019
 

Shield Therapeutics plc

("Shield" or the "Group")

 

Investor presentation

 

London, UK, 26 September 2019: Shield Therapeutics plc (LSE: STX), a commercial stage, pharmaceutical company with a focus on addressing iron deficiency with its lead product Feraccru®/AccruferTM (ferric maltol), announces that the Company will be hosting an investor presentation on Tuesday 12 November 2019.

 

The presentation will take place at The Copper Bar, 6 Adam's Court, Old Broad Street, London EC2N 1DX from 4.30pm for a 4.45pm start and will provide an opportunity for investors to hear about the progress being made by the Company.

 

If you would like to register, please contact Walbrook PR on 020 7933 8780 or email shield@walbrookpr.com.

 

No new material information will be disclosed at this event and the presentation will be made available on the Company's website here: https://www.shieldtherapeutics.com/presentations/

 

 

 

For further information please contact:

 

Shield Therapeutics plc

www.shieldtherapeutics.com

Carl Sterritt, Chief Executive Officer

+44 (0)20 7186 8500

Tim Watts, Chief Financial Officer

 

 

 

 

Nominated Advisor and Broker

 

Peel Hunt LLP

 

James Steel/Dr Christopher Golden

+44 (0)20 7418 8900

 

Joint Broker

finnCap Ltd     

Geoff Nash/Matt Radley/Alice Lane                                             

 

 

+44 (0)20 7220 0500

 

 

 

Financial PR & IR Advisor

 

Walbrook PR

+44 (0)20 7933 8780 or shield@walbrookpr.com

Paul McManus/Lianne Cawthorne

+44 (0)7980 541 893 / +44 (0)7584 391 303

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

About Shield Therapeutics plc

Shield is a de-risked, commercial stage, specialty pharmaceutical company delivering innovative pharmaceuticals to address patients' unmet medical needs.  The Company's clear purpose is to develop products that help patients become people again, enabling them to enjoy the things that make a difference in their everyday lives. The Group's lead product, Feraccru®/ AccruferTM has exclusive IP rights until the mid-2030s and is approved for the treatment of iron deficiency with or without anaemia in adults in the European Union, the United States and Switzerland.  In Europe it is marketed as Feraccru® with commercialisation led by Norgine BV and in the USA the product will be marketed as AccruferTM with Shield currently in the process of selecting a commercialisation partner. For more information please visit www.shieldtherapeutics.com

 

About Feraccru®/AccruferTM

Feraccru®/AccruferTM is a novel, stable, non-salt based oral therapy for adults with iron deficiency with or without anaemia that has been shown to be an efficacious and well-tolerated therapy in a range of controlled phase 3 trials, including positive results from the Phase IIIb AEGIS-H2H study in which Feraccru®/AccruferTM demonstrated it was non-inferior in delivering improvements in haemoglobin levels compared to intravenously-administered (IV) Ferinject®/Injectafer® (ferric carboxymaltose).  Feraccru®/AccruferTM therefore offers a compelling alternative to IV iron for those patients unable to tolerate salt-based oral iron therapies and wish to avoid the complexities of infusion-based iron therapies.

 

When salt-based oral iron therapies are ingested they can cause a range of mild-to-severe gastrointestinal tract (GI) adverse events, including nausea, bloating and constipation through the release and subsequent reactivity of free iron in the GI tract, leading to poor tolerability, reduced patient compliance and ultimately treatment failure.  Feraccru®/AccruferTM is not an iron salt and, as a result, it does not routinely cause the same treatment-limiting intolerance issues of salt-based iron therapies, whilst the iron from the ferric maltol molecule can be readily absorbed.

 

Prior to Feraccru®/AccruferTM, IV iron therapies were the only realistic alternative treatment option for iron deficient patients with or without anaemia intolerant of or unwilling to be treated salt-based oral iron therapies.  However, use of such an invasive, costly, inconvenient and complex to administer treatment option, which is associated with potentially life-threatening and spontaneous hypersensitivity reactions, means there remains a clear unmet medical need for these patients to have access to an effective therapy that is well tolerated, convenient and does not require hospital-based administration.  Feraccru®/AccruferTM meets those requirements.

 

About Iron Deficiency

The WHO states that iron deficiency is the most common and widespread nutritional disorder in the world.  As well as affecting a large number of women and children in non-industrialized countries, it is the only nutrient deficiency which is also significantly prevalent in virtually all industrialised nations.  There are no current global figures for iron deficiency but, using anaemia as an indirect indicator, it can be estimated that most preschool children and pregnant women in non-industrialised countries, together with at least 30-40% in industrialized countries, are iron deficient.

 

 

 

 


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